Development of Smart Transdermal Drug Delivery System for Controlled Release of Amphetamines Pharmaceuticals Formulation

Аннотация

This project focuses on the design and development of a smart transdermal drug delivery system for administering amphetamines, with a particular emphasis on its applications in addiction treatment and attention deficit hyperactivity disorder (ADHD) management. Amphetamines, including dextroamphetamine and methamphetamine, have shown therapeutic efficacy in addressing stimulant-related substance use disorders and ADHD symptoms. The proposed transdermal drug delivery system integrates advanced materials, microelectronics, and sensor technologies to optimise drug delivery, enhance patient adherence, and enable real-time monitoring of drug release and patient response. Through feasibility assessments, optimisation of drug release mechanisms, and evaluation of therapeutic efficacy, the project aims to advance understanding of transdermal delivery of amphetamines and its potential benefits in addiction treatment and ADHD management.

The project aims to advance smart transdermal drug delivery technologies to improve therapeutic outcomes and enhance patient experiences in addiction treatment and ADHD management. By offering convenient, non-invasive drug delivery and real-time monitoring capabilities, the system holds promise for addressing the complex healthcare needs of individuals with addiction and ADHD.

We've selected Transdermal Drug Delivery (TDD) for its painless systemic drug delivery through intact skin, providing non-invasiveness and placement flexibility.

To advance research in this area, we must address the significant ethical and regulatory considerations surrounding the use of controlled substances in clinical trials. Ultimately, the project aims to contribute to the advancement of drug delivery technologies and improve healthcare outcomes for individuals with addiction and ADHD.