THERAPY AND PREVENTION METHODS FOR ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN AND ADOLESCENTS

Abstract

The monograph is devoted to the actual problem of pediatric cardiology – essential arterial hypertension in children. Numerous scientific and applied research and practical developments in the aspects of risk factors, the course of diagnosis, method of treatment and prevention of essential arterial hypertension in children and adolescents were analyzed and summarized. Special emphasis is placed on diagnostic methods, methods of treatment and prevention of endothelial dysfunction in the development of essential arterial hypertension in children. The presented data expand the understanding of the mechanisms of the process of development of stable hypertension at the level of vascular endothelium, autonomic nervous system, and immune system in children. The criteria for the diagnosis of endothelium–dependent risk factors for the development of essential arterial hypertension in children based on associations of clinical, hemodynamic and immunological parameters are recommended. These diagnostic criteria made it possible to develop a method for the treatment and prevention of endothelial dysfunction in essential arterial hypertension in children and adolescents in primary health care.